Dr. Mel Lobo

Publications

Published Abstracts

Lobo, M., Ravic, N., Forte, P,. Milne, E., Lewis, G., Webb, A., Hedges, A.M., Benjamin, N. Effect of Quinapril and Losartan on Nitric Oxide Synthesis in Patients with Essential Hypertension. American Society of Hypertension. 2004.

Lobo, M., Zachary, I. Subcellular compartmentalisation, site-specific tyrosine phosphorylation and apoptotic proteolysis of Focal Adhesion Kinase in Human Umbilical Vein Endothelial Cells. Mol. Biol. Cell 1999 10:S, 335a

Lobo, M., Zachary, I. Constitutive nuclear localisation of Focal Adhesion Kinase in rabbit vascular smooth muscle cells. British Society for Cardiovascular Research. 1998

Lobo, M., Zachary, I. Increased protein expression of focal adhesion components during early stages of smooth muscle cell explant culture. 10th International Vascular Biology Meeting. 1998

Full publications

Lobo, M. Combined formulations in hypertension. Current thinking Supplement, Presciber Magazine July 2007

Lobo, M. State of the Art: Hypertension. The Practitioner (2002) 246, 408-414

Kabir, J., Lobo, M. Zachary, I. Staurosporine induces endothelial cell apoptosis via Focal Adhesion Kinase (FAK) dephosphorylation and focal adhesion disassembly independent of FAK proteolysis. Biochem. J. (2002) 367, 145-155

Abu-Ghazaleh, R., Kabir, J., Jia, H., Lobo, M., Zachary, I. Src mediates stimulation by vascular endothelial growth factor of the phosphorylation of Focal Adhesion Kinase at tyrosine 861, and migration and anti-apoptosis in endothelial cells. Biochem. J. (2001) 360, 255-264

Lobo, M., & Zachary, I. Nuclear localisation and apoptotic regulation of an amino-terminal domain focal adhesion kinase fragment in endothelial cells. Biochemical & Biophysical Research Communications, 276 (3):1068-1074, 2000 October 5

Cospedal, R., Lobo, M., Zachary, I. Differential regulation of ERKs 1 and 2 by cAMP and dissociation of ERK inhibition from anti-mitogenic effects in rabbit vascular smooth muscle cells. Biochem J (1999) 342, 407-414

Book chapters

Contributing author: Cardiovascular Sections (12 chapters), French' Index of Differential Diagnosis (15th Ed. In press 2005) Eds. Kinirons and Bouchier.

Case Reports

Ghadiri-Sana, M., Mann, I., Lobo, M., Jawad, A. Secondary syphilis presenting as palmoplantar psoriasis. Accepted for publication Journal of the RCP Edinburgh 2008

Rull G, Arunachalam G, Wadley J, Mandersloote G, Lobo M. Severe uncontrolled hypertension treated with microvascular decompression of the brainstem. Oral presentation British Hypertension Soc Annual Scientific Meeting 2007

Everett, CM., Turner, B., Lobo, M.Posterior reversible encephalopathy syndrome in (low renin) essential hypertension. J R Soc Med. 2007 Nov;100(11):522-3.

Donaldson, J., Knowles, C., Hughes, F., Lobo, M. Rectus sheath haematoma associated with low molecular weight heparin: a case series. Ann R Coll Surg Engl. 2007Apr;89(3):309-12.

Arunachalam, G., Emery, M., Lobo, M. A rugby player with collapse. Oral presentation European Federation of Internal Medicine 2007